An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. It may be either. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar. ameloblastic fibroma in a 9-year-old boy has been presented along with a review of the literature. The tumor responded to conservative surgical treatment.

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Ameloblastic fibroma: A rare case appearing as a mixed radiographic image

These findings underscore the need for a complete excision of the tumor as well as long-term clinical and radiographic follow up, with special attention given to cases of recurrences, which have a greater risk of malignant transformation 4. Case Reports in Pediatrics. A conservative approach, with excision followed by curettage, as performed in the present case, appears to be the most adequate treatment 3.

J Oral Maxillofac Pathol ; Case Report A year-old male was referred for evaluation of a lesion in the left body of the mandible identified in a radiographic exam for orthodontic treatment planning.

Ameloblastic fibroma – Wikipedia

Ameloblastic fibrosarcoma of the mandible: Discussion AF predominantly affects young patients, with a mean age of 15 years 2 – 4. We herein describe a massive AF involving mandible in a year-old female patient, suggestive of the neoplastic variant, with a special reference to its aspiration cytologic findings.

To the best of our knowledge, this is the first wmeloblastic presentation of a bilateral maxillary ameloblastic fibroma. Diagnosis Histological evaluation revealed multiple fragments of richly cellular mesenchymal tissue containing round drop-like islands and long narrow anastomosing cords of odontogenic epithelium.

A review of published studies with special reference to its nature and biological behavior. To conclude, we report a rare case of AF with high cellularity. Ossifying fibroma, extra-follicular variant of adenomatoid odontogenic tumor, calcifying cystic odontogenic tumor, calcifying epithelial odontogenic tumor, and myxoma were the main hypotheses of diagnosis. Report of a case with a special reference flbroma its aspiration cytologic findings.


Panoramic radiograph showed a unilocular radiolucent area with well-defined borders, involving the posterior aspect of the right mandible.

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In this brief report, we report a case of AF in the context of its high cellularity on histopathological examination. The epithelial component is made up of thin branching cords or small aameloblastic of odontogenic epithelium with little cytoplasm and basophilic nuclei. Microscopically AFs are composed of both the epithelial and connective tissue components; the later appears to recapitulate dental papilla made up of spindled and angular cells with delicate collagen, imparting a myxomatous appearance.

AF was first described by Krause in National Center for Biotechnology InformationU. Differential diagnosis of AF must also include entities such as ameloblastoma, odontogenic keratocyst, and ameloblastic fibrosarcoma [ 1213 ].

Published online Dec 1. In neoplastic cases, it may be labeled an ameloblastic fibrosarcoma in accord with the terminological distinction that reserves the word fibroma for benign tumors and assigns the word fibrosarcoma to malignant ones. Histopathologically, AF consists of odontogenic epithelium ameooblastic the dental papilla-like background without dental hard tissue formation.

A gland like epithelial component, arranged in well-outlined clusters of basaloid cells with palisading of the columnar cells at the borders of those clusters, and a mesenchymal component that consisted of loosely arranged fusiform cells.

A review of published studies amelolastic special reference to its nature and biological behavior. J Oral Pathol Med. The recurrence rate varies among sources, but is considered to be low [ 57 ]. Report of two cases. The panoramic radiography revealed a well-defined multilocular mixed image, with sclerotic borders, located in the mandible, laterally and between the roots of the left mandibular second premolar and first molar, measuring approximately 1.

Moreover, the epithelial islands observed in epithelium-rich odontogenic fibroma are immersed in a cellular fibroblastic connective tissue 6. Presently she is free from any recurrence.

Ameloblastic Fibroma

The ectomesenchymal component is composed of typical plump fibroblasts with delicate collagen fibrils simulating the dental papilla [ 24 ]. Abstract Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues.

Other clinical and radiographic clues are amelobkastic to narrow the diagnosis. Nevertheless, approximately two fibro,a of the ameloblastic fibrosarcomas representing malignant tumors de novo 8.


This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. Grossly, ameloblastic fibroma appears as firm, lobular soft tissue mass with a smooth surface [ 3 ]. Radiographically, AF appears as a well-defined unilocular or multilocular radiolucent image with a mean size of 4.

There stands a controversy on this spectrum of lesions whether these should be classified as different entities or represent different stages of maturation of the same entity. Sitemap What’s New Feedback Disclaimer. If dentin or enamel were noticed, they are classified as an ameloblastic fibrodentinoma or an ameloblastic fibroodontoma, respectively. Cortical expansion may or may not be discernable on plane film.

The overlying mucosa was intact. Jindal C, Bhola RS. In the past, it was suggested that these lesions represented a spectrum of a single entity, with ameloblastic fibromas, the least differentiated of the tumors, maturing and developing into ameloblastic fibro-odontomas and later odontomas [ 1 ].

National Center for Biotechnology FfibromaU. In addition, clinical and radiographic features are discussed as well as differential diagnosis and treatment.

The epithelium-rich odontogenic fibroma shows a variable amount of inactive odontogenic epithelial islands 6whereas the ameloblastic fibroma presents islands and strings of neoplastic epithelial cells, as occurred in this case.

However, the clinical manifestations of AF are not characteristic and the tumor is frequently observed as an incidental finding in a routine ffibroma examination [ 20 ].

Patient had identified the enlargement 8 months back and her medical history was unremarkable. The swelling caused labial and buccal cortical expansion bilaterally and extended up to the pterygoid plates along with palatal bone thickening.

Radiographically, AF appears as a well-defined, unilocular or multilocular radiolucent lesion, with sclerotic radiopaque margins 34. There were no carious or periodontal lesions in the left mandibular teeth.